The research in Sudlab integrates the use computational genomics with molecular cell biology, to answer questions about gene expression. We are particularly interested in post-transcriptional gene-regulation and how it is encoded in the sequence. The continuous scientific advances over the years have seen an increase in profiling of large numbers of tissues and cell samples, emphasizing the need of developing high-throughput techniques for analysing such complex data.
Sudlab uses bioinformatic and functional genomics tools to answer questions on splice variants, the effects of non-coding variants, transcript and protein expression levels etc. We are generally focused on the biological question, but will develop new tools and approaches where it is necessary.
Sudlab was established by Dr Ian Sudbery at the University of Sheffield, in 2014. It is now a thriving community of research staff and postgraduate students (MBiolSci, MSc and PhD).